The bioanalysis of PROTACs presents critical challenges—extremely low plasma concentrations, chemical instability, and lack of standardized assays make quantitative analysis complex and time-consuming. These issues hinder the rapid progression of groundbreaking therapeutics from discovery to clinic. Waters offers an integrated solution, delivering advanced LC-MS/MS technologies and automated sample prep workflows to overcome these obstacles with sensitivity, selectivity, and compliance.
This eBook details:
- Analytical hurdles in PROTAC discovery and development
- End-to-end sample prep and quantitation strategies
- Case studies demonstrating operational robustness
- Tools for untargeted and targeted metabolite analysis
- Compliant ready solutions with comprehensive audit trails
Discover how Waters empowers labs to accelerate innovation in PROTACs bioanalysis and deliver next-generation medicines with confidence.
